UNUSUAL METHYL TRANSFER IN THE BIOSYNTHESIS OF APORPHINE AND PROTOBERBERINE ALKALOIDS

被引：11

作者：

SCHNEIDER, B

ZENK, MH

机构：

[1] D-8000 München 2

来源：

PHYTOCHEMISTRY | 1993年 / 32卷 / 04期

关键词：

PEUMUS-BOLDUS; BERBERIS-STOLONIFERA; BERBERIDACEAE; CELL SUSPENSION CULTURES; C-13; NMR; RETICULINE; APORPHINES; PROTOBERBERINES; ALKALOIDS; BIOSYNTHESIS;

D O I：

10.1016/0031-9422(93)85226-H

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

(S)-Reticuline was triply-labelled with C-13 and administered to cell cultures of Peumus boldus and Berberis stolonifera, which are sources of aporphines and protoberberines, respectively. During incorporation of the labelled precursor into alkaloids of both groups, unexpected transmethylations of the methyl groups were observed by C-13 NMR spectroscopy which seem to proceed via demethylation, flux of C-13 through the C-1 pool, and remethylation.

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页码：897 / 903

页数：7

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