TRISOMY-7 MAY BE A PRIMARY CHANGE IN NONINVASIVE TRANSITIONAL CELL-CARCINOMA OF THE BLADDER

被引：15

作者：

BERROZPE, G

MIRO, R

CABALLIN, MR

SALVADOR, J

EGOZCUE, J

机构：

[1] UNIV AUTONOMA BARCELONA, DEPT BIOL CELLULAR & FISIOL, E-08193 BARCELONA, SPAIN

[2] UNIV AUTONOMA BARCELONA, FDN PUIGVERT, E-08193 BARCELONA, SPAIN

来源：

CANCER GENETICS AND CYTOGENETICS | 1990年 / 50卷 / 01期

关键词：

D O I：

10.1016/0165-4608(90)90232-Y

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We describe two cases of transitional cell carcinoma of the bladder associated with trisomy 7. In one of them, trisomy 7 was the only chromosomes abnormality observed. In the second case, trisomy 7 was found in 25 (80.6%) of the metaphases; in two of them this was the only anomaly, while in three metaphases trisomy 8 was also present, and in other two trisomy 10 was also observed. Our results suggest that trisomy 7 could be a primary change in TCC, and a review of the literature indicates that when it is present as the sole karyotypic abnormality is may be associated with a non-invasive behavior of the tumor. © 1990.

引用

页码：9 / 14

页数：6

共 19 条

[1] CYTOGENETIC STUDY OF 10 CARCINOMAS OF THE BLADDER - INVOLVEMENT OF CHROMOSOME-1 AND CHROMOSOME-11 [J].