GAP43 IDENTIFIES DEVELOPING MUSCLE-CELLS IN HUMAN EMBRYOS

被引：7

作者：

MOOS, T

CHRISTENSEN, LR

机构：

[1] UNIV COPENHAGEN,PANUM INST,CTR NEUROSCI,DK-2200 COPENHAGEN,DENMARK

[2] UNIV COPENHAGEN,PANUM INST,SCH DENT,DEPT ORTHODONT,DK-2200 COPENHAGEN,DENMARK

来源：

NEUROREPORT | 1993年 / 4卷 / 12期

关键词：

GAP43; B50; NEUROMODULIN; MYOTUBES; MYOBLASTS; NEUROMUSCULAR JUNCTION; MOTOR NERVE TERMINALS; EMBRYO; FETUS; HUMAN;

D O I：

10.1097/00001756-199309150-00003

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

GAP43 has long been regarded as a neurone specific molecule present intraneuronally in both the central and peripheral nervous system, especially during development and regeneration. GAP43 has, however, recently been demonstrated in developing muscle cells of the chicken. In the present investigation, we have used immunohistochemistry to investigate whether GAP43 is also expressed in developing human muscle cell. Using specific monoclonal antibodies as markers for developing muscle cells (desmin) and axon terminals (synaptophysin), our results show that GAP43 is expressed in aneural, human embryonic muscle cells.

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页码：1299 / 1302

页数：4

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