DETERMINATION OF BROMISOVAL AND CARBROMAL IN BIOLOGICAL MATERIAL

被引：5

作者：

RAUWS, AG

机构：

[1] National Institute of Public Health, Utrecht

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1969年 / 21卷 / 05期

关键词：

D O I：

10.1111/j.2042-7158.1969.tb08250.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The bromine determination (van der Meulen) has been adapted to the assay of bromisoval and carbromal in biological material. Interfering bromide is eliminated by pretreatment with silver nitrate. The ashing procedure was simplified by previous precipitation of proteins by acetone. Interference by bromine‐containing metabolites of the drugs is absent or minimal. The method is applicable in the range of 0·1 to 1 μmol. Recovery in blood was 95%. The standard deviation of the determination is approximately 5%. 1969 Royal Pharmaceutical Society of Great Britain

引用

页码：283 / &

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