IDENTIFICATION OF LY-5 ON THE SURFACE OF NATURAL KILLER CELLS IN NORMAL AND ATHYMIC INBRED MOUSE STRAINS

被引:63
作者
KASAI, M [1 ]
LECLERC, JC [1 ]
SHEN, FW [1 ]
CANTOR, H [1 ]
机构
[1] MEM SLOAN KETTERING CANC CTR,NEW YORK,NY 10021
关键词
D O I
10.1007/BF01561424
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
This report that (1) cells mediating NK activity in different inbred mouse strains selectively express one of two allelic products specified by the Ly-5 locus (or a locus tightly linked to it) and (2) this surface structure may directly contribute to NK-mediated cytolysis, since Ly 5 antiserum specifically inhibits NK activity in vitro in the absence of complement. © 1979 Springer-Verlag New York Inc.
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页码:153 / 159
页数:7
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