USE OF BHK CELL CULTURE-ADAPTED NEWCASTLE-DISEASE VIRUS FOR IMMUNIZATION OF CHICKS

被引：15

作者：

REDDY, GS ^{[1
]}

SRINIVASAN, VA ^{[1
]}

机构：

[1] INDIAN IMMUNOLOG,HYDERABAD 500133,INDIA

来源：

VACCINE | 1992年 / 10卷 / 03期

关键词：

NEWCASTLE DISEASE VIRUS; TISSUE CULTURE; ELISA; HEMAGGLUTINATION INHIBITION;

D O I：

10.1016/0264-410X(92)90006-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Newcastle disease virus mesogenic (Komarov) strain adapted to BHK21 suspension culture was used as a vaccine. The tissue culture-adapted virus was found to be potent and safe when administered to chicks by the intramuscular route. Potency was assessed by challenge test as well as by serology by haemagglutination inhibition and ELISA tests. The ELISA test appeared to be sensitive, efficacious and correlated well with the challenge test.

引用

页码：164 / 166

页数：3

共 8 条

[1]

ALLAN WH, 1969, RES VET SCI, V10, P222

[2]

BANKOWSKI R. A., 1958, AVIAN DIS, V2, P227, DOI 10.2307/1587523

[3] THE RELATIONSHIP BETWEEN THE HEMAGGLUTINATION-INHIBITION TEST AND THE ENZYME-LINKED-IMMUNOSORBENT-ASSAY FOR THE DETECTION OF ANTIBODY TO NEWCASTLE-DISEASE [J].