A CONVENIENT SYNTHESIS OF PLATELET-ACTIVATING FACTORS AND THEIR ANALOGS FROM CHIRAL EPICHLOROHYDRIN

被引：25

作者：

TSUBOI, S ^{[1
]}

TAKEDA, S ^{[1
]}

YAMASAKI, Y ^{[1
]}

SAKAI, T ^{[1
]}

UTAKA, M ^{[1
]}

ISHIDA, S ^{[1
]}

YAMADA, E ^{[1
]}

HIRANO, J ^{[1
]}

机构：

[1] NIPPON OIL & FATS CO LTD, TSUKUBA RES LAB, TOKODAI, TOKODAI 30026, JAPAN

来源：

CHEMISTRY LETTERS | 1992年 / 08期

关键词：

D O I：

10.1246/cl.1992.1417

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two platelet activating factors (PAF) were conveniently prepared from optically active epichlorohydrin via 5 steps in 15-16% total yield. Four analogues containing oleoyl, propyl, p-trifluoromethylphenoxy, and N,N-dimethyldithiocarbamoyl groups were also prepared.

引用

页码：1417 / 1420

页数：4

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