CHROMOSOMAL LOCALIZATION OF THE GAMMA-GLUTAMYL CARBOXYLASE GENE AT 2P12

被引：23

作者：

KUO, WL

STAFFORD, DW

CRUCES, J

GRAY, J

SOLERA, J

机构：

[1] UNIV N CAROLINA,DEPT BIOL,CHAPEL HILL,NC 27599

[2] UNIV N CAROLINA,CTR THROMBOSIS & HEMOSTASIS,CHAPEL HILL,NC 27599

[3] UNIV CALIF SAN FRANCISCO,DIV MOLEC CYTOMETRY,SAN FRANCISCO,CA 94103

[4] UNIV AUTONOMA MADRID,FAC MED,DEPT BIOQUIM,E-28029 MADRID,SPAIN

来源：

GENOMICS | 1995年 / 25卷 / 03期

关键词：

D O I：

10.1016/0888-7543(95)80024-G

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have used two complementary approaches to analyze the chromosomal location of the gamma-glutamyl carboxylase gene. The amplification of a carboxylase-specific genomic fragment by polymerase chain reaction (PCR) in a human-rodent hybrid cell mapping panel localized the gene to chromosome 2. Mapping by fluorescence in situ hybridization assigned the gene to p12 of chromosome 2. Our results indicate that the gamma-glutamyl carboxylase gene has a single locus in the human genome. (C) 1995 Academic Press, Inc.

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页码：746 / 748

页数：3

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