INHIBITORY ACTION OF GLYCINE ON RAT CORTICAL-NEURONS

被引：18

作者：

BERNARDI, G

CHERUBINI, E

MARCIANI, MG

STANZIONE, P

机构：

[1] Clinica delle Malattie Nervose e Mentali, Cattedra di Neuropsichiatria Infantile, Universita degli Studi di Roma, Rome

来源：

NEUROSCIENCE LETTERS | 1979年 / 12卷 / 2-3期

关键词：

D O I：

10.1016/0304-3940(79)96085-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat cortical inhibition is discussed. © 1979.

引用

页码：335 / 338

页数：4

共 11 条

[1] ACTION OF GABA ON RAT CAUDATE NEURONS RECORDED INTRACELLULARLY [J].

BERNARDI, G ;

MARCIANI, MG ;

MOROCUTTI, C ;

GIACOMINI, P .

BRAIN RESEARCH, 1975, 92 (03) :511-515

[2]

BISCOE T J, 1972, Comparative and General Pharmacology, V3, P423, DOI 10.1016/0010-4035(72)90056-0

[3]

BRUGGENCATE G T, 1968, Brain Research, V11, P446

[4]

CURTIS DR, 1968, EXP BRAIN RES, V5, P235

[5] EFFECTS OF GLYCINE ON SPINAL NEURONES GROWN IN TISSUE CULTURE [J].

HOSLI, L ;

ANDRES, PF ;

HOSLI, E .

BRAIN RESEARCH, 1971, 34 (02) :399-&

[6] ACTION OF GLYCINE ON CORTICAL NEURONES [J].

KELLY, JS ;

KRNJEVIC, K .

EXPERIMENTAL BRAIN RESEARCH, 1969, 9 (02) :155-&

[7] ACTION OF GAMMA-AMINOBUTYRIC ACID ON CORTICAL NEURONES [J].

KRNJEVIC, K ;

SCHWARTZ, S .

EXPERIMENTAL BRAIN RESEARCH, 1967, 3 (04) :320-&

[8] UNIQUE HIGH AFFINITY UPTAKE SYSTEMS FOR GLYCINE, GLUTAMIC AND ASPARTIC ACIDS IN CENTRAL NERVOUS TISSUE OF RAT [J].

LOGAN, WJ ;

SNYDER, SH .

NATURE, 1971, 234 (5327) :297-&

[9] DEVELOPMENTAL TRANSITIONS IN UPTAKE OF AMINO-ACIDS BY SYNAPTOSOMAL FRACTIONS ISOLATED FROM RAT CEREBRAL-CORTEX [J].

PETERSON, NA ;

RAGHUPATHY, E .

JOURNAL OF NEUROCHEMISTRY, 1973, 21 (01) :97-110

[10] INHIBITORY ACTION OF GLYCINE ON SPINAL NEURONS IN CAT [J].

WERMAN, R ;

DAVIDOFF, RA ;

APRISON, MH .

JOURNAL OF NEUROPHYSIOLOGY, 1968, 31 (01) :81-&

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