NEAR-HAPLOIDY IN A CASE OF CHRONIC MYELOID-LEUKEMIA

被引：30

作者：

HARTLEY, SE ^{[1
]}

COOK, MK ^{[1
]}

机构：

[1] BANGOUR GEN HOSP,DEPT HAEMATOL,BROXBURN,W LOTHIAN,SCOTLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1979年 / 1卷 / 02期

关键词：

D O I：

10.1016/0165-4608(79)90022-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A case of Philadelphia chromosome positive chronic myeloid leukemia is reported in which the patient developed a near-haploid cell line during blast transformation. Although there was only one copy of most chromosomes, two copies of chromosomes 8, X, and 21 were present and the significance of this is discussed. It is postulated that a haploid event rather than chromosome loss was responsible for this. It was not associated with a particularly aggressive course of the disease. The relationship between the near-haploidy and cellular morphology is examined. © 1979.

引用

页码：169 / 176

页数：8

共 15 条

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[9] 2-4
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