INTERLEAVED H-1 AND P-31 SPECTROSCOPIC IMAGING FOR STUDYING REGIONAL BRAIN INJURY

被引：13

作者：

CHANG, LH

COHEN, Y

WEINSTEIN, PR

CHILEUITT, L

JAMES, TL

机构：

[1] Department of Pharmaceutical Chemistry, University of California, San Francisco

[2] Department of Neurosurgery, University of California, San Fraciso

[3] Department of Radiology, University of California, San Francisco

来源：

MAGNETIC RESONANCE IMAGING | 1991年 / 9卷 / 02期

关键词：

H-1; NMR; P-31; SPATIAL LOCALIZATION; CHEMICAL SHIFT IMAGING; BRAIN ISCHEMIA;

D O I：

10.1016/0730-725X(91)90014-D

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We present a new approach for in vivo localized spectroscopy which combines H-1 and P-31 one-dimensional spectroscopic imaging pulse sequences in an interleaved, time-shared manner using a surface coil. This approach was used to acquire metabolic information from a rat brain with regional ischemia at 4.7 Tesla. Spectra with very good signal-to-noise ratios, void of chemical shift artifacts, are obtainable from voxel sizes less than 0.3 cm3 in 40 min. Advantages and drawbacks of the proposed methodology are discussed.

引用

页码：223 / 227

页数：5

共 21 条

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