USING FLUORESCENCE INSITU HYBRIDIZATION (FISH) IN GENOME MAPPING

被引：29

作者：

KORENBERG, JR

YANGFENG, T

SCHRECK, R

CHEN, XN

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,LOS ANGELES,CA 90048

[2] YALE UNIV,DEPT HUMAN GENET,NEW HAVEN,CT 06511

来源：

TRENDS IN BIOTECHNOLOGY | 1992年 / 10卷 / 1-2期

关键词：

D O I：

10.1016/0167-7799(92)90163-P

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fluorescence in situ hybridization (FISH) provides one of the most effective and rapid approaches for assigning and ordering DNA fragments within single eukaryotic chromosome bands. These techniques have wide applications not only for the mapping of the human genome and the genomes of other organisms, but also in clinical cytogenetics, somatic cell genetics, cancer diagnosis and gene expression studies1-4.

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页码：27 / 32

页数：6

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