LOCALIZATION OF MESSENGER-RNA FOR PHOSPHATIDYLINOSITOL 3-KINASE IN BRAIN OF DEVELOPING AND MATURE RATS

被引：14

作者：

ITO, Y ^{[1
]}

GOTO, K ^{[1
]}

KONDO, H ^{[1
]}

机构：

[1] TOHOKU UNIV,SCH MED,DEPT ANAT,AOBA KU,SENDAI,MIYAGI 980,JAPAN

来源：

MOLECULAR BRAIN RESEARCH | 1995年 / 34卷 / 01期

关键词：

PHOSPHATIDYLINOSITOL; 3-KINASE; IN SITU HYBRIDIZATION; RAT; BRAIN; DEVELOPMENT;

D O I：

10.1016/0169-328X(95)00153-J

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the adult brain, the gene expression for phosphatidylinositol 3-kinase was weak in almost all neurons with relatively high levels in the olfactory bulb, hippocampus, and cerebellum. On the embryonic days high levels of the gene expression were found throughout the entire neuraxis, then decreased gradually to adult levels during postnatal development. The present finding suggests that phosphatidylinositol 3-kinase may contribute not only to neurogenesis but also to some important physiological roles in differentiating and mature neurons.

引用

页码：149 / 153

页数：5

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