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EFFECTS OF PULMONARY REHABILITATION ON PHYSIOLOGICAL AND PSYCHOSOCIAL OUTCOMES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY-DISEASE

被引：598
作者：
RIES, AL
KAPLAN, RM
LIMBERG, TMK
PREWITT, LM
机构：
[1] University of California, San Diego, San Diego, CA
[2] Div. Pulmon. and Critical Care Med., University of California, San Diego, Medical Center, San Diego, CA 92103-8377
[3] University of California, San Diego, San Diego, CA 92093
来源：
ANNALS OF INTERNAL MEDICINE | 1995年 / 122卷 / 11期
关键词：
LUNG DISEASES; OBSTRUCTIVE; REHABILITATION; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); EXERCISE; BREATHING EXERCISES;
D O I：
10.7326/0003-4819-122-11-199506010-00003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To compare the effects of comprehensive pulmonary rehabilitation with those of education alone on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease. Design: Randomized clinical trial. Setting: University medical center. Patients: 119 outpatients with chronic obstructive pulmonary disease that was stable while patients received a standard medical regimen. Intervention: Patients were randomly assigned to either an 8-week comprehensive pulmonary rehabilitation program or to an 8-week education program. Pulmonary rehabilitation consisted of twelve 4-hour sessions that included education, physical and respiratory care instruction, psychosocial support, and supervised exercise training. Monthly reinforcement sessions were held for 1 year. The education group attended four 2-hour sessions that included videotapes, lectures, and discussions but not individual instruction or exercise training. Measurements: Pulmonary function, maximum exercise tolerance and endurance, gas exchange, symptoms of perceived breathlessness and muscle fatigue with exercise, shortness of breath, self-efficacy for walking, depression, general quality of well-being, and hospitalizations associated with pulmonary diseases. Patients were followed for 6 years. Results: Compared with education alone, comprehensive pulmonary rehabilitation produced a significantly greater increase in maximal exercise tolerance (+1.5 metabolic equivalents [METS] compared with +0.6 METS [P < 0.001]; maximal oxygen uptake, +0.11 L/min compared with +0.03 L/min [P = 0.06]), exercise endurance (+10.5 minutes compared with +1.3 minutes [P < 0.001]), symptoms of perceived breathlessness (score of -1.5 compared with +0.2 [P < 0.001]) and muscle fatigue (score of -1.4 compared with -0.2 [P < 0.01]), shortness of breath (score of -7.0 compared with +0.6 [P < 0.01]), and self-efficacy for walking (score of +1.4 compared with +0.1 [P < 0.05]). There were slight but nonsignificant differences in survival (67% compared with 56% [P = 0.32]) and duration of hospital stay (-2.4 days/patient per year compared with +1.3 days/patient per year [P = 0.20]). Measures of lung function, depression, and general quality of life did not differ between groups. Differences tended to diminish after 1 year of follow-up. Conclusions: Comprehensive pulmonary rehabilitation significantly improved exercise performance and symptoms for patients with moderate to severe chronic obstructive pulmonary disease. Benefits were partially maintained for at least 1 year and tended to diminish after that time.
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页码：823 / 832
页数：10
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