DETERMINATION OF CALCIUM IN PHARMACEUTICAL PREPARATIONS BY ATOMIC ABSORPTION SPECTROMETRY

被引:8
作者
DALRYMPLE, BA
KENNER, CT
机构
[1] Food and Drug Administration, Dallas, Texas, 75204, Dallas District
关键词
Atomic absorption spectroscopy—analysis; Calcium determination—pharmaceuticals; Capsule absorption—active components; Lanthanum—assay interference elimination;
D O I
10.1002/jps.2600580521
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Atomic absorption spectrometry is applied to the determination of calcium in pharmaceutical samples using both the direct method and the method of standard additions. Comparison with the standard chelometric method using EDTA and hydroxy naphthol blue indicates that the atomic absorption methods require less time and are equivalent to the chelometric method in precision and accuracy. The majority of interferences are eliminated by the addition of one percent lanthanum to the solutions. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码:604 / +
页数:1
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