LIPID-PEROXIDATION IN PIGMENTED AND UNPIGMENTED LIVER-TISSUES - PROTECTIVE ROLE OF MELANIN

被引：68

作者：

SCALIA, M ^{[1
]}

GEREMIA, E ^{[1
]}

CORSARO, C ^{[1
]}

SANTORO, C ^{[1
]}

BARATTA, D ^{[1
]}

SICHEL, G ^{[1
]}

机构：

[1] UNIV CATANIA,INST GEN BIOL,VIA ANDRONE 81,I-95124 CATANIA,ITALY

来源：

PIGMENT CELL RESEARCH | 1990年 / 3卷 / 02期

关键词：

Antioxidant pigment; Frog liver; Rat liver;

D O I：

10.1111/j.1600-0749.1990.tb00330.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The protective role of melanin as an antioxidant biopolymer against lipid peroxidation was investigated. In pigmented frog liver and in albino rat liver the following were tested: thiobarbituric acid (TBA) reactive material (to show the induced lipoperoxidation in vitro), fatty acids, and reduced glutathione content. Our results show that susceptibility to the in vitro lipoperoxidation induced by ferrous ions is lower in the tissue containing melanin, though the content of the polyunsaturated fatty acids is higher in pigmented than in unpigmented tissues and reduced glutathione levels are lower in pigmented tissue. Our data support the hypothesis that melanin could reduce lipoperoxidation in pigmented tissue. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：115 / 119

页数：5

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