DIASTOLIC VENTRICULAR-FUNCTION IN TYPE-1 DIABETIC-PATIENTS - A STUDY USING DOPPLER ECHOCARDIOGRAPHY

被引：15

作者：

GROSSMANN, G

SCHMIDT, A

HAUNER, H

GOLLER, V

STAUCH, M

PFEIFFER, EF

HOMBACH, V

机构：

[1] Abteilung für Kardiologie, Medizinischen Klinik und Poliklinik, Universität Ulm

[2] Abteilung für Endokrinologie, Medizinischen Klinik und Poliklinik, Universität Ulm

[3] Abteilung Für Sportmedizin, Medizinischen Klinik Und Poliklinik, Universität Ulm

来源：

DIABETIC MEDICINE | 1991年 / 8卷 / 03期

关键词：

LEFT VENTRICULAR DIASTOLIC FUNCTION; DOPPLER ECHOCARDIOGRAPHY; TRANSMITRAL DIASTOLIC FLOW VELOCITY; TYPE-1; DIABETES;

D O I：

10.1111/j.1464-5491.1991.tb01573.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The transmitral flow velocity pattern of 28 Type 1 diabetic patients and 39 age-matched healthy control subjects was studied for determination of left ventricular diastolic function. No patient had systemic hypertension, congestive heart failure, or ischaemic heart disease by clinical or electrocardiographic criteria. Echocardiographic measures of systolic ventricular function were within normal range in all subjects. The ratio of early to late transmitral peak flow velocity (V(e)/V(a)) was significantly decreased in the diabetic patients (1.3 +/- 0.1 (+/- SE) vs 1.6 +/- 0.1, p < 0.05), while other Doppler derived variables did not show any significant difference. No correlation of V(e)/V(a) with duration of diabetes was found (r = 0.27), but it correlated with age in both groups (both r = -0.40, p < 0.05). Furthermore, a significant correlation was found between V(e)/V(a) and heart rate (r = -0.55 for diabetic patients, p < 0.01; r = -0.58 for control subjects, p < 0.01). After matching for heart rate (24 diabetic patients and 24 control subjects) no significant decrease of V(e)/V(a) was observed in the diabetic group.

引用

页码：208 / 212

页数：5

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