INTRAOPERATIVE MEASUREMENT OF THE GRAFT OXYGENATION STATE IN LIVING-RELATED LIVER-TRANSPLANTATION BY NEAR-INFRARED SPECTROSCOPY

被引：19

作者：

KITAI, T

TANAKA, A

TOKUKA, A

SATO, B

MORI, S

YANABU, N

INOMOTO, T

UEMOTO, S

TANAKA, K

YAMAOKA, Y

OZAWA, K

SOMEDA, H

FUJIMOTO, M

MORIYASU, F

HIRAO, K

机构：

[1] Second Department of Surgery, Faculty of Medicine, Kyoto University, Kyoto, 606, 54 Kawara-cho, Shogoin, Sakyo-ku

[2] First Department of Medicine, Faculty of Medicine, Kyoto University, Kyoto, 606, 54 Kawara-cho, Shogoin, Sakyo-ku

[3] Otsuka Electronics, Shiga

来源：

TRANSPLANT INTERNATIONAL | 1995年 / 8卷 / 02期

关键词：

VIABILITY; INFRARED SPECTROSCOPY; LIVER; LIVING RELATED LIVER TRANSPLANTATION; LIVER TRANSPLANTATION; LIVING RELATED DONATION;

D O I：

10.1007/BF00344420

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Graft oxygenation plays an important role in successful liver transplantation. Intraoperative changes in the oxygenation state of the liver graft were measured by near infrared spectroscopy in 28 cases of living related liver transplantation. Oxygen saturation of hemoglobin in the liver (hepatic SO2) changed from 81.2 % +/- 1.5 % (mean +/- SEM) before donation (in the donor) to 49.7 % +/- 4.2 % after portal reflow, to 58.4 % +/- 5.0 % after arterial reflow, and then to 71.4 % +/- 3.9 % before closure. Mean hepatic SO2 was positively correlated with portal flow rate as measured by duplex Doppler sonography. Cases with low portal flow rate showed a high coefficient of variation (SD/mean) of hepatic SO2, indicating heterogeneous tissue oxygenation. Though graft size was expected to affect the graft oxygenation state, hepatic SO2 was fairly independent of the graft-to-recipient weight ratio. In two cases with markedly low hepatic SO2, postoperative graft dysfunction occurred. This study suggest that the method of near infrared spectroscopy is reliable and useful for assessing the graft oxygenation state in liver transplantation.

引用

页码：111 / 118

页数：8

共 26 条

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