EXPERIMENTAL RETINECTOMY IN THE RABBIT

被引：7

作者：

HUTCHINS, RK ^{[1
]}

DAMICO, DJ ^{[1
]}

CASEY, VNJ ^{[1
]}

MORIN, B ^{[1
]}

机构：

[1] HARVARD UNIV,MASSACHUSETTS EYE & EAR INFIRM,SCH MED,DEPT OPHTHALMOL,RETINA SERV,243 CHARLES ST,BOSTON,MA 02114

来源：

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 1990年 / 10卷 / 01期

关键词：

Retinal detachment proliferative vitreoretinopathy; Retinectomy; Retinotomy; Vitrectomy;

D O I：

10.1097/00006982-199001010-00014

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We developed a model for creating retinectomies of various sizes in phakic rabbit eyes and examined the effects of retinal attachment, epiretinal membrane formation, and intraocular pressure. Eleven retinectomized eyes with an average defect size of 5.6 disc areas and a postoperative followup from 48 to 62 days remained attached without retinopexy, and pigmented scarring involving the photoreceptor/retinal pigment epithelial layers was observed at the margins of the retinectomy. No sign of epiretinal membrane formation was detected by ophthalmoscopic or histologic examination. Postoperative ocular tensions were similar between retinectomized and unoperated control eyes. This experimental study in the avascular rabbit retina suggests that retinectomies do not invariably cause epiretinal membranes or ocular hypotension. © The Ophthalmic Communications Society, Inc.

引用

页码：72 / 77

页数：6

共 11 条

[1] Freeman W.R., Henderly D.E., Wan W.L., Et al., Prevalence, pathophysiology, and treatment of rhegmatogenous retinal detachment in treated cytomegalovirus retinitis, Am J Ophthalmol, 103, pp. 527-536, (1987)
[2] Machemer R., Retinotomy, Am J Ophthalmol, 92, pp. 768-774, (1981)
[3] Machemer R., Schneiden der Netzhaut. Eine Behandlungsmoeglichkeit zur Wiederanlegung der Netzhaut, Klin Monastbl Augenheilkd, 175, pp. 587-601, (1979)
[4] Machemer R., McCuen B.W., De Juan E., Relaxing retinotomies and retinectomies, Am J Ophthalmol, 102, pp. 7-12, (1986)
[5] Parke D.W., Aaberg T.M., Intraocular argon laser photocoagulation in the management of severe proliferative vitreoretinopathy, Am J Ophthalmol, 97, pp. 434-443, (1984)
[6] Zivojnovic R., Mertens D.A.E., Peperkamp E., Das fluessige slikon in der amotiochirurgie (II). Bericht ueber 280 faelleweitere entwicklung der technik, Klin monastbl augenheilkd, 181, pp. 444-452, (1982)
[7] Machemer R., Norton E.W.D., Experimental retinal detachment in the owl monkey. I. Methods of production and clinical picture, Am J Ophthalmol, 66, pp. 388-396, (1968)
[8] Macdonald S.G., Buzney S.M., Verstraeten T.C., Migration of bare RPE and formation of preretinal membranes in vivo, ARVO Abstracts, Invest Ophthalmol Vis Sci, 27, (1986)
[9] Miller B., Miller H., Patterson R., Ryan S.J., Retinal wound healing. Cellular activity at the vitreoretinal interface, Arch Ophthalmol, 104, pp. 281-285, (1986)
[10] Foulds W.S., Experimental retinal detachment, Trans Ophth Soc UK, 83, pp. 153-170, (1963)

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