Lowering Glucose to Prevent Adverse Cardiovascular Outcomes in a Critical Care Setting

被引：39

作者：

Ceriello, Antonio ^{[1
]}

Zarich, Stuart W. ^{[2
]}

Testa, Roberto ^{[3
]}

机构：

[1] Univ Warwick, Warwick Med Sch, Ctr Excellence Diabet & Endocrinol, Univ Hosp Coventry & Warwickshire, Coventry CV4 7AL, W Midlands, England

[2] Yale Univ, Sch Med, Div Cardiovasc Med, Bridgeport Hosp, Bridgeport, CT USA

[3] INRCA Ancona, Dept Gerontol Res, Diabetol Unit, Ancona, Italy

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2009年 / 53卷 / 05期

关键词：

ACUTE MYOCARDIAL-INFARCTION; TIGHT GLYCEMIC CONTROL; RANDOMIZED CONTROLLED-TRIAL; INSULIN-POTASSIUM INFUSION; C-REACTIVE PROTEIN; FREE FATTY-ACIDS; DIABETES-MELLITUS; ILL PATIENTS; VENTRICULAR ARRHYTHMIAS; STRESS HYPERGLYCEMIA;

D O I：

10.1016/j.jacc.2008.09.054

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

High admission blood glucose levels after acute myocardial infarction are common and associated with an increased risk of death in patients with or without diabetes. Hyperglycemia is associated with altered myocardial blood flow and energetics and can lead to a pro-oxidative/proinflammatory state. The use of intensive insulin treatment has shown superior benefits in the treatment of hyperglycemia versus glucose-insulin-potassium infusion, particularly in critical care settings. (J Am Coll Cardiol 2009;53:S9-13) (C) 2009 by the American College of Cardiology Foundation

引用

页码：S9 / S13

页数：5

共 44 条

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