ONLINE ANION-EXCHANGE PURIFICATION OF [N-13] NH3 PRODUCED BY 10 MEV PROTON IRRADIATION OF DILUTE AQUEOUS-ETHANOL

被引：6

作者：

BORMANS, G ^{[1
]}

LANGENDRIES, W ^{[1
]}

MORTELMANS, L ^{[1
]}

VERBRUGGEN, A ^{[1
]}

机构：

[1] UNIV HOSP GASTHUISBERG,B-3000 LOUVAIN,BELGIUM

来源：

APPLIED RADIATION AND ISOTOPES | 1995年 / 46卷 / 02期

关键词：

D O I：

10.1016/0969-8043(94)00105-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

[13N]NH3 prepared by irradiating dilute aqueous ethanol with 10 MeV protons is contaminated with small amounts of [18F]fluoride and [13N]NO2 -/NO3 -. The content of 18F is negligible at end of bombardment but increases as a function of time due to the longer half-life of 18F. We developed a simple on-line purification method in which the irradiated water directly passes through a small anion exchange column. Both the radionuclidic impurity [18F]fluoride and the radiochemical impurities [13N]NO3 -/NO2 - are efficiently removed by this procedure which results in highly pure (>99.9%) [13N]NH3 preparations. © 1995.

引用

页码：83 / 86

页数：4

共 12 条

[1]

BIDA G, 1986, J LABELLED COMPD RAD, V23, P1217

[2] DIRECT COMPARISON OF [N-13] AMMONIA AND [O-15]WATER ESTIMATES OF PERFUSION WITH QUANTIFICATION OF REGIONAL MYOCARDIAL BLOOD-FLOW BY MICROSPHERES [J].

BOL, A ;

MELIN, JA ;

VANOVERSCHELDE, JL ;

BAUDHUIN, T ;

VOGELAERS, D ;

DEPAUW, M ;

MICHEL, C ;

LUXEN, A ;

LABAR, D ;

COGNEAU, M ;

ROBERT, A ;

HEYNDRICKX, GR ;

WIJNS, W .

CIRCULATION, 1993, 87 (02) :512-525

[3]

BORMANS G, 1993, EUR J NUCL MED, V20, P862

[4] NONINVASIVE QUANTIFICATION OF REGIONAL BLOOD-FLOW IN THE HUMAN HEART USING N-13 AMMONIA AND DYNAMIC POSITRON EMISSION TOMOGRAPHIC IMAGING [J].

HUTCHINS, GD ;

SCHWAIGER, M ;

ROSENSPIRE, KC ;

KRIVOKAPICH, J ;

SCHELBERT, H ;

KUHL, DE .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1990, 15 (05) :1032-1042

[5] QUANTIFICATION OF REGIONAL MYOCARDIAL BLOOD-FLOW USING N-13 AMMONIA AND REORIENTED DYNAMIC POSITRON EMISSION TOMOGRAPHIC IMAGING [J].

KUHLE, WG ;

PORENTA, G ;

HUANG, SC ;

BUXTON, D ;

GAMBHIR, SS ;

HANSEN, H ;

PHELPS, ME ;

SCHELBERT, HR .

CIRCULATION, 1992, 86 (03) :1004-1017

[6]

MULHOLLAND GK, 1990, APPL RADIAT ISOTOPES, V41, P1193

[7]

MUZIK O, 1993, J NUCL MED, V34, P83

[8]

PARKS NJ, 1975, INT J APPL RADIAT IS, V29, P754

[9]

Sajjad M., 1985, RADIO CHIMICA ACTA, V38, P57, DOI [10.1524/ract.1985.38.2.57, DOI 10.1524/RACT.1985.38.2.57]

[10] IMPROVED METHOD FOR CYCLOTRON PRODUCTION OF N-13-LABELLED AMMONIA [J].

VAALBURG, W ;

KAMPHUIS, JAA ;

BEERLINGVANDERMOLEN, HD ;

REIFFERS, S ;

RIJSKAMP, A ;

WOLDRING, MG .

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1975, 26 (05) :316-318

← 1 2 →