学术探索
学术期刊
新闻热点
数据分析
智能评审

PARENTAL IMPRINTING OF AUTOSOMAL MAMMALIAN GENES

被引：200
作者：
EFSTRATIADIS, A
机构：
[1] Department of Genetics and Development, Columbia University, New York, NY 10032
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 02期
关键词：
D O I：
10.1016/S0959-437X(05)80054-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The molecular mechanisms introducing epigenetic modifications that lead to differential silencing of some autosomal alleles depending on their parental legacy are still largely unknown, but recent results from studies of endogenously imprinted genes and particular transgenes make DNA methylation a strong candidate. At the same time, these results have raised new questions about the details of the imprinting process.
引用
收藏
页码：265 / 280
页数：16
相关论文
共 137 条
  • [1] BAKER J, 1993, CELL, V75, P73, DOI 10.1016/0092-8674(93)90680-O
  • [2] METHYLATION AND IMPRINTING - FROM HOST DEFENSE TO GENE-REGULATION
    BARLOW, DP
    [J]. SCIENCE, 1993, 260 (5106) : 309 - 310
  • [3] THE MOUSE INSULIN-LIKE GROWTH-FACTOR TYPE-2 RECEPTOR IS IMPRINTED AND CLOSELY LINKED TO THE TME LOCUS
    BARLOW, DP
    STOGER, R
    HERRMANN, BG
    SAITO, K
    SCHWEIFER, N
    [J]. NATURE, 1991, 349 (6304) : 84 - 87
  • [4] PARENTAL IMPRINTING OF THE MOUSE H19 GENE
    BARTOLOMEI, MS
    ZEMEL, S
    TILGHMAN, SM
    [J]. NATURE, 1991, 351 (6322) : 153 - 155
  • [5] EPIGENETIC MECHANISMS UNDERLYING THE IMPRINTING OF THE MOUSE H19-GENE
    BARTOLOMEI, MS
    WEBBER, AL
    BRUNKOW, ME
    TILGHMAN, SM
    [J]. GENES & DEVELOPMENT, 1993, 7 (09) : 1663 - 1673
  • [6] CYTOSINE METHYLATION - THE PROS AND CONS OF DNA METHYLATION
    BESTOR, TH
    COXON, A
    [J]. CURRENT BIOLOGY, 1993, 3 (06) : 384 - 386
  • [7] THE ESSENTIALS OF DNA METHYLATION
    BIRD, A
    [J]. CELL, 1992, 70 (01) : 5 - 8
  • [8] GENOMIC IMPRINTING - IMPRINTS ON ISLANDS
    BIRD, AP
    [J]. CURRENT BIOLOGY, 1993, 3 (05) : 275 - 277
  • [9] THE ONTOGENY OF ALLELE-SPECIFIC METHYLATION ASSOCIATED WITH IMPRINTED GENES IN THE MOUSE
    BRANDEIS, M
    KAFRI, T
    ARIEL, M
    CHAILLET, JR
    MCCARREY, J
    RAZIN, A
    CEDAR, H
    [J]. EMBO JOURNAL, 1993, 12 (09) : 3669 - 3677
  • [10] THE PRODUCT OF THE H19 GENE MAY FUNCTION AS AN RNA
    BRANNAN, CI
    DEES, EC
    INGRAM, RS
    TILGHMAN, SM
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (01) : 28 - 36
12345678910