INDUCTION OF MURICIDAL BEHAVIOR BY ACTH OR ADRENALECTOMY IN YOUNG MALE WISTAR RATS

被引:7
作者
MIACHON, S
CLAUSTRAT, B
CESPUGLIO, R
机构
[1] CTR HOSP LYON SUD, HOP NEUROL,CNRS,URA 1195,INSERM,U52, NEUROCHIM FONCT LAB, F-69310 PIERRE BENITE, FRANCE
[2] FAC MED ROCKEFELLER, LYON, FRANCE
关键词
MURICIDE; AGGRESSIVE; RATS; ACTH; ADRENALECTOMY;
D O I
10.1016/0361-9230(94)00175-Z
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
ACTH administered IP induces a muricidal behavior in 52% of male Wistar rats that do not express it before; such behavior is also observed spontaneously in 68% of adrenalectomized animals. This change in behavior is characterized by an exceptionally long duration (several months in some animals), and by its prevention by previous or substitutive treatments with dexamethasone. Data obtained using hypophysectomized or adrenalectomized animals with or without ACTH treatments suggest that the muricidal-inducing effect of ACTH might have, at least partially, a central origin.
引用
收藏
页码:119 / 123
页数:5
相关论文
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