ACETOGENIC ISOQUINOLINE ALKALOIDS .16. ON THE STRUCTURE OF THE DIONCOPHYLLACEAE ALKALOIDS DIONCOPHYLLINE-A (TRIPHYOPHYLLINE) AND O-METHYL-TRIPHYOPHYLLINE

被引：85

作者：

BRINGMANN, G ^{[1
]}

RUBENACKER, M ^{[1
]}

JANSEN, JR ^{[1
]}

SCHEUTZOW, D ^{[1
]}

ASSI, LA ^{[1
]}

机构：

[1] UNIV ABIDJAN,CTR NATL FLORIST,ABIDJAN 22,COTE IVOIRE

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)94588-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The naphthyl isoquinoline alkaloid "triphyophylline" is structurally re-investigated. The constitution, as well as the relative configurations at C-1 and C-3, are confirmed as published previously. "Triphyophylline" is found to be a stable rotational isomer with respect to the biaryl linkage, the absolute configuration at the stereogenic axis is determined to be S. The data of the natural product "O-methyl-triphyophylline", as reported in the literature, are shown not to be identical with those of the O-methylation product of triphyophylline, as prepared by partial synthesis. This inconsistency within the published series of Dioncophyllaceae alkaloids necessitates to rename "triphyophylline" (new name: "dioncophylline A"). © 1990.

引用

页码：639 / 642

页数：4

共 15 条

[1] ACETOGENIC ISOQUINOLINE ALKALOIDS .17. 1ST TOTAL SYNTHESIS OF (-)-DIONCOPHYLLINE-A (TRIPHYOPHYLLINE) AND OF SELECTED STEREOISOMERS - COMPLETE (REVISED) STEREOSTRUCTURE [J].