STRUCTURE OF 1-[(4-ACETAMIDOPHENYL)THIO]-3-[4-(3-METHYLPHENYL)PIPERAZIN-L-YL]PROPANE MONOHYDRATE

被引：2

作者：

CARPY, A ^{[1
]}

LEGER, JM ^{[1
]}

RAO, J ^{[1
]}

SAXENA, AK ^{[1
]}

机构：

[1] CENT DRUG RES INST,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1991年 / 47卷

关键词：

D O I：

10.1107/S0108270191008089

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

C22H29N3OS.H2O, M(r) = 401.57, monoclinic, P2(1)/c, a = 6.511 (1), b = 14.914 (3), c = 22.550 (4) angstrom, beta = 97.84 (1)-degrees, V = 2169.1 angstrom 3, Z = 4, D(x) = 1.23 g cm-3, lambdaBAR(Cu K-alpha) = 1.54178 angstrom, mu = 14.59 cm-1, F(000) = 864, room temperature, R = 0.058 for 1270 observed reflections. This compound is a centrally active hypotensive agent. The molecule can be described by two planar moieties, i.e. the methylphenyl group and the [(4-acetamidophenyl)thio]propane group substituting a piperazine ring in a chair conformation. The overall conformation is trans extended.

引用

页码：2704 / 2706

页数：3

共 6 条

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