STABILITY OF MALIGNANT BREAST MICROCALCIFICATIONS

被引:48
作者
LEVTOAFF, AS
FEIG, SA
SAITAS, VL
FINKEL, GC
SCHWARTZ, GF
机构
[1] THOMAS JEFFERSON UNIV HOSP,DEPT PATHOL,PHILADELPHIA,PA 19107
[2] THOMAS JEFFERSON UNIV HOSP,DEPT SURG,PHILADELPHIA,PA 19107
关键词
BREAST; CALCIFICATION; BREAST NEOPLASMS; DIAGNOSIS;
D O I
10.1148/radiology.192.1.8208928
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To determine the frequency of stability in malignant microcalcifications and its relationship to specific histologic diagnoses. MATERIALS AND METHODS: During a 34-month period, microcalcifications were proved malignant in 182 patients referred for needle-guided biopsy. In 105 patients, the mammograms were compared with one or more than one previous mammogram. These patients were classified on the basis of interval change in two groups: those with stable and those with increasing or new microcalcifications. The histologic diagnoses were reviewed. RESULTS: Microcalcifications were stable for 8-63 months (mean, 25.4 months) in 26 patients (24.8%), only three (12%) of whom had invasive ductal carcinoma, Which was found in 29 (37%) of the 79 patients with increasing or new microcalcifications. CONCLUSION: The odds for presence of invasive ductal carcinoma are statistically significantly lower (P < .025) among patients with stable microcalcifications than among those with increasing or new microcalcifications. Stability of indeterminate or suspicious microcalcifications is unreliable for exclusion of a diagnosis of malignancy.
引用
收藏
页码:153 / 156
页数:4
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