STRUCTURE ELUCIDATION AND SYNTHESIS OF 3-BETA,6-ALPHA-DIHYDROXY-9-OXO-9,11-SECO-5-ALPHA-CHOLEST-7-EN-11-AL, A NOVEL 9,11-SECOSTEROL FROM THE SPONGE SPONGIA-OFFICINALIS

被引：40

作者：

MIGLIUOLO, A ^{[1
]}

PICCIALLI, V ^{[1
]}

SICA, D ^{[1
]}

机构：

[1] UNIV NAPLES,DIPARTIMENTO CHIM ORGAN & BIOL,VIA MEZZOCANNONE 16,I-80134 NAPLES,ITALY

来源：

TETRAHEDRON | 1991年 / 47卷 / 37期

关键词：

D O I：

10.1016/S0040-4020(01)81948-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel 9,11-secosterol, 3-beta,6-alpha-dihydroxy-9-oxo-9,11-seco-5-alpha-cholest-7-en-11-al (1), has been isolated from the marine sponge Spongia officinalis and its structure deduced by analysis of spectral data including H-1 NMR COSY and H-1-C-13 correlation NMR experiments. The structure of 1 was confirmed by synthesis starting from 7-dehydrocholesterol.

引用

页码：7937 / 7950

页数：14

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