HYDROLYSIS OF PHOSPHATE MONOESTERS - A BIOLOGICAL PROBLEM WITH MULTIPLE CHEMICAL SOLUTIONS

被引：313

作者：

VINCENT, JB ^{[1
]}

CROWDER, MW ^{[1
]}

AVERILL, BA ^{[1
]}

机构：

[1] UNIV VIRGINIA, DEPT CHEM, CHARLOTTESVILLE, VA 22901 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 03期

关键词：

D O I：

10.1016/0968-0004(92)90246-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Formation of phosphate esters by kinases has long been recognized as an important process in biochemistry, but the reverse reaction, hydrolysis of phosphate esters by phosphatases, has attracted less attention. Recent work suggests that phosphatases are as important as kinases in regulatory processes, and that they constitute a diverse group of enzymes that utilize a variety of chemical means to accelerate phosphate ester hydrolysis.

引用

页码：105 / 110

页数：6

共 31 条

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