THE ANTIINFLAMMATORY AND LIVER PROTECTIVE EFFECT OF TITHONIA-DIVERSIFOLIA (HEMSL) GRAY AND DICLIPTERA-CHINENSIS JUSS EXTRACTS IN RATS

被引：18

作者：

LIN, CC

LIN, ML

LIN, JM

机构：

[1] School of Pharmacy, Kaohsiung Medical College, Kaohsiung

来源：

PHYTOTHERAPY RESEARCH | 1993年 / 7卷 / 04期

关键词：

ANTIINFLAMMATORY EFFECT; LIVER PROTECTION; TITHONIA-DIVERSIFOLIA (HEMSL) GRAY; DICLIPTERA-CHINENSIS JUSS; EXTRACTS;

D O I：

10.1002/ptr.2650070409

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antiinflammatory and liver protective effect of water extracts of Tithonia diversifolia (Hemsl.) Gray (aerial part), T. diversifolia (stem) and Dicliptera chinensis Juss. (aerial part) against paw oedema induced by carrageenan and acute hepatic damage induced by CCl4 were determined in rats. The results indicated that treatment with a water extract of the aerial part of T. diversifolia decreased the paw oedema induced by carrageenan (p<0.001) and the GOT, GPT level elevation caused by CCl4 were reduced (p<0.01). The pathological changes of hepatic lesions caused by CCl4 were improved by treatment with the drug extracts mentioned above.

引用

页码：305 / 309

页数：5

共 27 条

[1] DIVERSE EFFECTS OF SKF 525-A AND ANTIOXIDANTS ON CARBON TETRACHLORIDE-INDUCED CHANGES IN LIVER MICROSOMAL P-450 CONTENT AND ETHYLMORPHINE METABOLISM
CASTRO, JA
SASAME, HA
SUSSMAN, H
GILLETTE, JR
[J]. LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY, 1968, 7 (3P1): : 129 - &
[2] THE PHARMACOLOGICAL AND PATHOLOGICAL-STUDIES ON SEVERAL HEPATIC PROTECTIVE CRUDE DRUGS FROM TAIWAN .1.
CHIU, HF
LIN, CC
YANG, CC
YANG, F
[J]. AMERICAN JOURNAL OF CHINESE MEDICINE, 1988, 16 (3-4): : 127 - 137
[3] THE PHARMACOLOGICAL AND PATHOLOGICAL-STUDIES ON SEVERAL HEPATIC PROTECTIVE CRUDE DRUGS FROM TAIWAN(II)
CHIU, HF
LIN, CC
YANG, CC
YANG, F
[J]. AMERICAN JOURNAL OF CHINESE MEDICINE, 1989, 17 (1-2): : 17 - 23
[4] CHIU HF, 1992, AM J CHINESE MED, V4, P257
[5] MEDIATORS OF INFLAMMATION INDUCED IN RAT PAW BY CARRAGEENIN
CRUNKHORN, P
MEACOCK, SCR
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1971, 42 (03) : 392 - +
[6] STUDIES OF MEDIATORS OF ACUTE INFLAMMATORY RESPONSE INDUCED IN RATS IN DIFFERENT SITES BY CARRAGEENAN AND TURPENTINE
DIROSA, M
GIROUD, JP
WILLOUGHBY, DA
[J]. JOURNAL OF PATHOLOGY, 1971, 104 (01) : 15 - +
[7] MECHANISM OF INFLAMMATORY EFFECT OF CARRAGEENIN
DIROSA, M
SORRENTINO, L
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1968, 4 (03) : 340 - +
[8] FERREIRA SH, 1974, BRIT J PHARMACOL, V52, P108
[9] EFFECTS OF ANTIINFLAMMATORY DRUGS ON PROSTAGLANDIN BIOSYNTHESIS
FLOWER, R
VANE, JR
GRYGLEWS.R
HERBACZY.K
[J]. NATURE-NEW BIOLOGY, 1972, 238 (82): : 104 - &
[10] CRITICAL ROLE OF LIPID PEROXIDATION IN CARBON TETRACHLORIDE-INDUCED LOSS OF AMINOPYRINE DEMETHYLASE, CYTOCHROME-P-450 AND GLUCOSE 6-PHOSPHATASE
GLENDE, EA
HRUSZKEWYCZ, AM
RECKNAGEL, RO
[J]. BIOCHEMICAL PHARMACOLOGY, 1976, 25 (19) : 2163 - 2170

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