POLYRIBOSOME CONCENTRATION OF MOUSE SKELETAL MUSCLE AS A FUNCTION OF AGE

被引：54

作者：

SRIVASTAVA, U

机构：

[1] Biomedical Center, Faculty of Medicine, Laval University, Quebec, P.Q.

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1969年 / 130卷 / 1-2期

关键词：

D O I：

10.1016/0003-9861(69)90018-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Incorporation of phenylalanine into protein of mouse skeletal muscle decreases with age of mouse. This change in muscle is accompanied by a progressive decline in the concentration of polysemes and total RNA content in the pH-5-enzyme fraction. These conclusions are based on the results of two types of experiments: (a) by measuring the incorporation of phenylalanine by microsomes in the presence and in the absence of poly-U; (b) by comparing the sucrose density gradient distribution of ribosomal preparations which were separately treated with poly-U and ribonuclease. © 1969.

引用

页码：129 / +

页数：1

共 11 条

[1] AMINO ACID INCORPORATION INTO PROTEIN BY CELL-FREE PREPARATIONS FROM RAT SKELETAL MUSCLE .2. PREPARATION + PROPERTIES OF MUSCLE RIBOSOMES + POLYRIBOSOMES [J].