AN EXTREMELY SIMPLE, CONVENIENT, AND SELECTIVE METHOD FOR ACETYLATING PRIMARY ALCOHOLS IN THE PRESENCE OF SECONDARY ALCOHOLS

被引：201

作者：

ISHIHARA, K ^{[1
]}

KURIHARA, H ^{[1
]}

YAMAMOTO, H ^{[1
]}

机构：

[1] NAGOYA UNIV,SCH ENGN,NAGOYA 46401,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 15期

关键词：

D O I：

10.1021/jo00067a005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of primary-secondary diols with acetyl chloride in dichloromethane in the presence of 2,4,6-collidine, NN-diisopropylethylamine, or 1,2,2,6,6-pentamethylpiperidine (PMP) leads to the corresponding primary monoacetates simply, conveniently, and in good yields. In this way, other acyl chlorides, sulfonyl chlorides, and silyl chlorides in place of acetyl chloride also react with primary hydroxyl group selectively.

引用

页码：3791 / 3793

页数：3

共 13 条

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