GLYCEROL SOURCE FOR BIOSYNTHESIS OF ALKYL GLYCERYL ETHERS

被引：60

作者：

WYKLE, RL

SNYDER, F

机构：

[1] Medical Division3 3 Under contract with the U. S. Atomic Energy Commission., Oak Ridge Associated Universities Oak Ridge

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 37卷 / 04期

关键词：

D O I：

10.1016/0006-291X(69)90861-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have used a specific inhibitor to distinguish between glyceraldehyde-3-P and dihydroxyacetone-P as the glycerol source of alkyl glyceryl ethers. Only dihydroxyacetone-P reacted with fatty alcohols in the presence of the inhibitor and microsomes from preputial gland tumors to produce the O-alkyl linkage (CoA, ATP, and Mg++ are essential cofactors). The products formed have chromatographic properties consistent with the reaction sequence proposed by us in an earlier paper. © 1969.

引用

页码：658 / &

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