HIGH-ENERGY PHOSPHATE-COMPOUNDS AND SOME GLYCOLYTIC SUBSTRATES IN THE RAT-BRAIN DURING HYPOXIA

被引：3

作者：

BRONISZEWSKAARDELT, B

SIKORSKA, M

机构：

[1] Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences

来源：

JOURNAL OF NEUROSCIENCE RESEARCH | 1979年 / 4卷 / 04期

关键词：

glycolytic substrates; high‐energy phosphates; hypoxic brain;

D O I：

10.1002/jnr.490040404

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The influence of acute and prolonged (with resuscitation) hypoxia, upon some glycolytic substrates and high energy phosphate compounds in the rat brain, was studied. Acute hypoxia decreased the content of glucose and glucose‐6‐phosphate as well as of high energy phosphate compounds. Simultaneously, an increase of lactic acid level was recorded. Some adaptation features could be observed, when 30‐minute hypoxia with resuscitation was studied. Brain content of high energy compounds returned to the normal value, while that of glucose increased twice over control. However, the level of lactic acid was still increased. Copyright © 1979 Alan R. Liss, Inc.

引用

页码：261 / 264

页数：4

共 9 条

[1]

ASTRUP P, 1960, LANCET, V1, P1035

[2]

BALAZS R, 1970, HDB NEUROCHEMISTRY, P2

[3] CEREBRAL CARBOHYDRATE METABOLISM DURING ACUTE HYPOXIA AND RECOVERY [J].