THE PRODUCTION OF A HUMAN MONOCLONAL-ANTIBODY DEFINING A SPLIT OF HLA-DRW13 (DRW13B)

被引：4

作者：

BUNCE, M

SUTTON, PM

TING, A

MORRIS, PJ

机构：

[1] Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford

来源：

TISSUE ANTIGENS | 1990年 / 36卷 / 03期

关键词：

D O I：

10.1111/j.1399-0039.1990.tb01808.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Abstract: By use of the heterohybridoma technique we have produced a human monoclonal antibody (NDS40) which detects a split of HLA‐DRwl 3 (DRwl3b) which is in linkage with HLA‐DQwl. In addition, the antibody reacts with cells positive for HLA‐DRw8 and DRwl 1, but does not react with the commonly found split of DRw1 3 (DRw1 3a) which is associated with DQwl. NDS40 is cytotoxic and is of the lambda IgM class. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：100 / 102

页数：3

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