DELAYED WALLERIAN DEGENERATION IN SCIATIC-NERVES OF C57BL/OLA MICE IS ASSOCIATED WITH IMPAIRED REGENERATION OF SENSORY AXONS

被引：112

作者：

BISBY, MA

CHEN, S

机构：

[1] Department of Physiology, Queen's University, Kingston, Ont.

来源：

BRAIN RESEARCH | 1990年 / 530卷 / 01期

关键词：

C57BL/Ola mouse; Regeneration; Sensory axon; W#allerian degeneration;

D O I：

10.1016/0006-8993(90)90666-Y

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Wallerian degeneration is delayed following sciatic nerve crush in C57BL/Ola mice. Compared to C57BL/6J mice, regeneration of sensory axons is significantly slowed in the Ola mice, but reinnervation does eventually occur. We conclude that Wallerian degeneration is a prerequisite for normal sensory axon regeneration following a crush injury to peripheral nerve. © 1990.

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页码：117 / 120

页数：4

相关论文

共 15 条

[1]

BROWN MC, UNPUB CONSEQUENCES N

[2] THE EFFECT OF INHIBITING SCHWANN-CELL MITOSIS ON THE RE-INNERVATION OF ACELLULAR AUTOGRAFTS IN THE PERIPHERAL NERVOUS-SYSTEM OF THE MOUSE [J].

HALL, SM .

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 1986, 12 (04) :401-414

[3] CHANGES OF NERVE GROWTH-FACTOR SYNTHESIS IN NONNEURONAL CELLS IN RESPONSE TO SCIATIC-NERVE TRANSECTION [J].

HEUMANN, R ;

KORSCHING, S ;

BANDTLOW, C ;

THOENEN, H .

JOURNAL OF CELL BIOLOGY, 1987, 104 (06) :1623-1631

[4] LIPOPROTEIN UPTAKE BY NEURONAL GROWTH CONES INVITRO [J].

IGNATIUS, MJ ;

SHOOTER, EM ;

PITAS, RE ;

MAHLEY, RW .

SCIENCE, 1987, 236 (4804) :959-962

[5] EXPRESSION AND POSSIBLE FUNCTION OF NERVE GROWTH-FACTOR RECEPTORS ON SCHWANN-CELLS [J].

JOHNSON, EM ;

TANIUCHI, M ;

DISTEFANO, PS .

TRENDS IN NEUROSCIENCES, 1988, 11 (07) :299-304

[6] INTERLEUKIN-1 REGULATES SYNTHESIS OF NERVE GROWTH-FACTOR IN NONNEURONAL CELLS OF RAT SCIATIC-NERVE [J].

LINDHOLM, D ;

HEUMANN, R ;

MEYER, M ;

THOENEN, H .

NATURE, 1987, 330 (6149) :658-659

[7] ABSENCE OF WALLERIAN DEGENERATION DOES NOT HINDER REGENERATION IN PERIPHERAL-NERVE [J].

LUNN, ER ;

PERRY, VH ;

BROWN, MC ;

ROSEN, H ;

GORDON, S .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1989, 1 (01) :27-33

[8] EXPRESSION OF THE NEURAL CELL-ADHESION MOLECULES L1 AND N-CAM AND THEIR COMMON CARBOHYDRATE EPITOPE L2/HNK-1 DURING DEVELOPMENT AND AFTER TRANSECTION OF THE MOUSE SCIATIC-NERVE [J].

NIEKE, J ;

SCHACHNER, M .

DIFFERENTIATION, 1985, 30 (02) :141-151

[9] NERVE GROWTH ACTIVITIES IN RAT PERIPHERAL-NERVE [J].

RICHARDSON, PM ;

EBENDAL, T .

BRAIN RESEARCH, 1982, 246 (01) :57-64

[10] PERIPHERAL-NERVE CONTAINS HETEROGENEOUS GROWTH-FACTORS THAT SUPPORT SENSORY NEURONS INVITRO [J].

RIOPELLE, RJ ;

BOEGMAN, RJ ;

CAMERON, DA .

NEUROSCIENCE LETTERS, 1981, 25 (03) :311-316