THE PROGNOSTIC-SIGNIFICANCE OF HISTOLOGIC REGRESSION IN CUTANEOUS MELANOMA

被引：35

作者：

BROGELLI, L

UMBERTO, MR

MORETTI, S

URSO, C

机构：

[1] Clinica Dermatologica II, University of Firenze, Firenze, 50121

[2] Chirurgia Plastica e Ricostruttiva, University of Firenze

[3] Istituto Anatomia e Istologia Patologica, University of Firenzes

来源：

MELANOMA RESEARCH | 1992年 / 2卷 / 02期

关键词：

PROGNOSIS; REGRESSION;

D O I：

10.1097/00008390-199207000-00002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A retrospective evaluation of 201 stage I cutaneous melanomas was performed to investigate the prognostic significance of histological regression (present in 67 cases). Thin melanomas showed regression more frequently than thick lesions (48% less-than-or-equal-to 0.75 mm vs 12% > 3 mm). The mean disease-free interval was 33.53 months in regressing tumours and 19.9 in non-regressing tumours (p=0.07): differences between the survival curves were not significant (p=0.61). Metastases developed in 13 (19.40%) patients with regressing tumours and by 40 (29.85%) patients with non-regressing tumours. Although we observed a higher frequency of regression in thin melanomas we could not demonstrate an influence of regression on disease-free interval and survival.

引用

页码：87 / 91

页数：5

共 10 条

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