THE COST-EFFECTIVENESS OF HELICOBACTER-PYLORI ERADICATION VERSUS MAINTENANCE AND EPISODIC TREATMENT IN DUODENAL-ULCER PATIENTS IN SWEDEN

被引：33

作者：

UNGE, P

JONSSON, B

STALHAMMAR, NO

机构：

[1] Sandviken Hospital, Sandviken

[2] Stockholm School of Economics, Stockholm

[3] Astra Hassle AB, Mölndal

来源：

PHARMACOECONOMICS | 1995年 / 8卷 / 05期

关键词：

D O I：

10.2165/00019053-199508050-00005

中图分类号：

F [经济];

学科分类号：

02 ;

摘要：

This study compares the cost effectiveness of Helicobacter pylori eradication and conventional treatment in duodenal ulcer patients treated by a general practitioner. Using a Markov chain approach, Swedish cost data and a study period of 5 years, we conclude that H. pylori eradication with omeprazole and appropriate antibiotics is a cost-effective alternative compared with both maintenance and episodic treatment. Of the patients entering the eradication strategy, most an cured and will have no relapse during a 5-year period. H. pylori eradication results in higher initial costs but, because of a very low risk of recurrence after successful eradication, the expected future costs are reduced. The investment pays off within 1 year when compared with maintenance treatment, and within 3 years when compared with episodic treatment.

引用

页码：410 / 427

页数：18

共 28 条

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