INHIBITION OF HUMAN ERYTHROCYTE CALPAIN-I BY NOVEL QUINOLINE CARBOXAMIDES

被引:19
作者
GRAYBILL, TL [1 ]
DOLLE, RE [1 ]
OSIFO, IK [1 ]
SCHMIDT, SJ [1 ]
GREGORY, JS [1 ]
HARRIS, AL [1 ]
MILLER, MS [1 ]
机构
[1] STERLING WINTHROP PHARMACEUT RES DIV, DEPT BIOCHEM, COLLEGEVILLE, PA 19426 USA
关键词
D O I
10.1016/0960-894X(95)00041-Q
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.
引用
收藏
页码:387 / 392
页数:6
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