PHARMACOKINETICS OF KETANSERIN AND ITS METABOLITE KETANSERIN-OL IN MAN AFTER INTRAVENOUS, INTRAMUSCULAR AND ORAL-ADMINISTRATION

被引：40

作者：

HEYKANTS, J ^{[1
]}

VANPEER, A ^{[1
]}

WOESTENBORGHS, R ^{[1
]}

GOULD, S ^{[1
]}

MILLS, J ^{[1
]}

机构：

[1] JANSSEN PHARMACEUT,DEPT CLIN PHARMACOL,WANTAGE,ENGLAND

来源：

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1986年 / 31卷 / 03期

关键词：

D O I：

10.1007/BF00981135

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：343 / 350

页数：8

共 26 条

[1] NONCOMPARTMENTAL DETERMINATION OF THE STEADY-STATE VOLUME OF DISTRIBUTION [J].

BENET, LZ ;

GALEAZZI, RL .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (08) :1071-1074

[2]

DECREE J, 1981, LANCET, V1, P1161

[3]

DECREE J, 1984, LANCET, V2, P775

[4]

DECREE J, 1985, J CARDIOVASC PHARM, V7, pS126

[5] INTERACTION OF KETANSERIN AND ITS METABOLITE KETANSERINOL WITH 5HT2 RECEPTORS IN PULMONARY AND CORONARY-ARTERIES OF CALF [J].

FRENKEN, M ;

KAUMANN, AJ .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1984, 326 (04) :334-339

[6]

GIBALDI M, 1982, PHARMACOKINETICS

[7] KETANSERIN, A NOVEL 5-HYDROXYTRYPTAMINE ANTAGONIST - MONOTHERAPY IN ESSENTIAL-HYPERTENSION [J].

HEDNER, T ;

PERSSON, B ;

BERGLUND, G .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 16 (02) :121-125

[8] KETANSERIN IN COMBINATION WITH BETA-ADRENERGIC-RECEPTOR BLOCKING-AGENTS IN THE TREATMENT OF ESSENTIAL-HYPERTENSION [J].

HEDNER, T ;

PERSSON, B .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 18 (05) :765-771

[9]

JANSSEN PAJ, 1985, J CARDIOVASC PHARM, V7, pS2

[10] BIOAVAILABILITY AND PHARMACOKINETICS OF KETANSERIN IN ELDERLY SUBJECTS [J].

KUROWSKI, M .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 28 (04) :411-417

← 1 2 3 →