SELECTIVE SUPPRESSION OF CEREBRAL EVOKED POTENTIALS TO PATTERNED LIGHT IN AMBLYOPIA EX ANOPSIA

Experimental evidence is presented to show that there is an abnormal depression of the computer derived visual evoked response to patterned images when they are presented to the amblyopic eye in a significant number of children with amblyopia ex anopsia. In contrast, no differences of significance were seen in the VERs obtained by stimulating the normal and amblyopic eyes individually with plain light. A specific inhibition of pattern vision is postulated. When this evidence is evaluated in the light of the known fact that cells uniquely sensitive to shape are found only in the cortex, then the cortex (rather than the retina or geniculate body) appears to be the most likely site of the defect in human amblyopia ex anopsia. © 1969.