ULTRASTRUCTURAL EVENTS IN EARLY CALCIUM-OXALATE CRYSTAL-FORMATION IN RATS

被引：31

作者：

DYKSTRA, MJ ^{[1
]}

HACKETT, RL ^{[1
]}

机构：

[1] UNIV FLORIDA,SCH MED,DEPT PATHOL,GAINESVILLE,FL 32610

来源：

KIDNEY INTERNATIONAL | 1979年 / 15卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/ki.1979.84

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A model system is described for the induction of renal calcium oxalate crystals with intraperitoneal of sodium oxalate in rats. Early crystals are formed predominantly in cortical areas. Massive amounts of calcium are associated with this process, as demonstrated by potassium pyroantimonate staining. Actual crystal formation appears to be an involved process associated with calcium, oxalate, and cellular membranes. Although overt stone formation was not observed, the authors feel that the intimate involvement of membranes during crystal formation may be similar to that found in renal stones.

引用

页码：640 / 650

页数：11

共 38 条

[1] ORGANIC MATRIX OF HUMAN URINARY CONCRETIONS [J].

BOYCE, WH .

AMERICAN JOURNAL OF MEDICINE, 1968, 45 (05) :673-&

[2] THE AMOUNT AND NATURE OF THE ORGANIC MATRIX IN URINARY CALCULI - A REVIEW [J].

BOYCE, WH ;

GARVEY, FK .

JOURNAL OF UROLOGY, 1956, 76 (03) :213-227

[3] USE OF POTASSIUM PYROANTIMONATE IN LOCALIZATION OF SODIUM IONS IN RAT KIDNEY TISSUE [J].

BULGER, RE .

JOURNAL OF CELL BIOLOGY, 1969, 40 (01) :79-&

[4]

COE FL, 1978, NEPHROLITHIASIS PATH, pCH2

[5]

CORNELIUS CE, 1960, J UROL, V89, P223

[6] ELECTRON-MICROSCOPIC LOCALIZATION OF CALCIUM IN VASCULAR SMOOTH-MUSCLE [J].

DEBBAS, G ;

HOFFMAN, L ;

LANDON, EJ ;

HURWITZ, L .

ANATOMICAL RECORD, 1975, 182 (04) :447-471

[7]

DOREMUS RH, 1978, INVEST UROL, V15, P469

[8]

DOREMUS RH, 1972, UROLITHIASIS PHYSICA, P193

[9] INVESTIGATION OF MICROSTRUCTURE OF KIDNEY STONES (OXALATE TYPE) BY HIGH-VOLTAGE ELECTRON-MICROSCOPY AND ELECTRON-DIFFRACTION [J].

ELSAYED, K ;

COSSLETT, VE .

EXPERIENTIA, 1977, 33 (07) :919-921

[10]

FINLAYSON B, 1978, INVEST UROL, V15, P442

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