REDUCTIVE RING-OPENING OF EPHEDRINE AND PSEUDOEPHEDRINE-DERIVED OXAZOLIDINIUM METHIODIDES BY SODIUM-BOROHYDRIDE - A DIRECT ACCESS TO NEW CHIRAL AMINE-BORANE ADDUCTS

被引：11

作者：

ANDRES, C ^{[1
]}

DELGADO, M ^{[1
]}

PEDROSA, R ^{[1
]}

机构：

[1] UNIV VALLADOLID,FAC CIENCIAS,DEPT QUIM ORGAN,DR MERGELINA S-N,E-47011 VALLADOLID,SPAIN

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 06期

关键词：

D O I：

10.1080/00397919208020847

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sodiun borohydride reacts with oxazolidinium methiodides derived from ephedrine and pseudoephedrine, in ethereal solvents, cleaving regioselectively the C-N bond of the ring and leading, in good yields, to chiral amine-borane adducts of know absolute configuration. The 1HNMR data allow to predict the most stable conformation.

引用

页码：829 / 839

页数：11

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