INVESTIGATION OF NORMAL AND ACNE SKIN SURFACE LIPIDS

被引：14

作者：

RUNKEL, RA

WURSTER, DE

COOPER, GA

机构：

[1] School of Pharmacy, University of Wisconsin, Madison, Wisconsin

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 05期

关键词：

Acne; normal skin—surface lipid acidity; GLC—analysis; IR spectrophotometry—analysis; Microbiological analysis—artificial sebum; Skin surface lipids—analysis;

D O I：

10.1002/jps.2600580514

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Human skin surface lipid samples from both acne patients and normal individuals were examined with respect to both total acidity and the detailed composition of the free acid fraction. On the basis of this study, there is no apparent relationship between the total acidity of the surface lipid and the severity of the acne condition, nor is there a gross difference in the composition of the free acid fraction between the normal and the acne condition. Corynebacterium acnes has been cultured in a medium containing certain glycerides normally found in sebum and its esterase activity established. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：582 / &

共 20 条

[1] THE FATTY ACID COMPOSITION OF THE SURFACE SKIN FATS (SEBUM) IN ACNE VULGARIS AND SEBORRHEIC DERMATITIS [J].