DIRECTION OF POLARITY OF MITOCHONDRIAL TRANS-MEMBRANE POTENTIAL

被引：53

作者：

HARRIS, EJ

PRESSMAN, BC

机构：

[1] Johnson Foundation, University of Pennsylvania, Philadelphia, PA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 172卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0005-2728(69)90092-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The concentration of various anions in the sucrose impermeable space of ratliver mitochondria relative to the applied concentration can be used to calculate an equilibrium potential if one supposes that the anion distribution is passive. Values so calculated for anions of different net charge are about 30 mV, with the interior positive. The relative merits of the hypotheses that an internal positivity is generated by active cation movement or Mitchell's chemiosmotic generation of an internal negativity coupled with hydroxyl-for-anion exchanges are examined. © 1969.

引用

页码：66 / &

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