RESIN GLYCOSIDES .9. OPERCULIN-I, OPERCULIN-II, OPERCULIN-V, OPERCULIN-VII AND OPERCULIN-VIII, NEW ETHER-SOLUBLE RESIN GLYCOSIDES OF RHIZOMA JALAPAE-BRAZILIENSIS (THE ROOTS OF IPOMOEA-OPERCULATA)

被引:29
作者
ONO, M [1 ]
NISHI, M [1 ]
KAWASAKI, T [1 ]
MIYAHARA, K [1 ]
机构
[1] SETSUNAN UNIV, FAC PHARMACEUT SCI, 45-1 NAGAOTOGE CHO, HIRAKATA, OSAKA 57301, JAPAN
关键词
Convolvulaceae ether-soluble resin glycoside macrocyclic ester structure operculin I operculin II operculin V operculin VII operculin VIII; resin glycoside; Rhizoma Jalapae Braziliensis;
D O I
10.1248/cpb.38.2986
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Eight ether-soluble resin glycosides (jalapins), operculins I—VIII, were isolated from Rhizoma Jalapae Braziliensis (the roots of Ipomoea operculata). Among them, the structures of operculins I, II, V, VII and VIII, which have a common glycosidic acid, operculinic acid A, have been determined on the basis of chemical and spectral data. Similar to the jalapins so far isolated from several Convolvulaceae plants, all of them have intramolecular macrocyclic ester structures. They have n-dodecanoic and/or n-decanoic acid as a component organic acid in place of hitherto known isobutyric, 2-methylbutyric, tiglic and nilic acids. © 1990, The Pharmaceutical Society of Japan. All rights reserved.
引用
收藏
页码:2986 / 2991
页数:6
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