IDENTIFICATION OF TEM-26 BETA-LACTAMASE RESPONSIBLE FOR A MAJOR OUTBREAK OF CEFTAZIDIME-RESISTANT KLEBSIELLA-PNEUMONIAE

被引：58

作者：

URBAN, C

MEYER, KS

MARIANO, N

RAHAL, JJ

FLAMM, R

RASMUSSEN, BA

BUSH, K

机构：

[1] NYU,SCH MED,DEPT MICROBIOL,NEW YORK,NY 10016

[2] ALBERT EINSTEIN COLL MED,NEW YORK,NY 10461

[3] BRISTOL MYERS SQUIBB CO,DEPT MICROBIOL,WALLINGFORD,CT 06492

[4] AMER CYANAMID CO,DIV MED RES,PEARL RIVER,NY 10965

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 02期

关键词：

D O I：

10.1128/AAC.38.2.392

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An epidemic of nosocomial ceftazidime-resistant Klebsiella pneumoniae was correlated with production of a ceftazidime-hydrolyzing enzyme with an isoelectric point of 5.6 (BMH-1). BMH-1 was encoded on a large transferable plasmid conferring multiple antibiotic resistance. The gene that encodes BMH-1 was identical to the gene that encodes the TEM-26 extended-spectrum beta-lactamase.

引用

页码：392 / 395

页数：4

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