NO SIGNIFICANT INCREASE IN SISTER-CHROMATID EXCHANGES IN CULTURED BLOOD-LYMPHOCYTES FROM WORKERS IN A LARGE OIL REFINERY

被引：16

作者：

KHALIL, AM

QASSEM, W

KAMAL, OM

机构：

[1] YARMOUK UNIV,HIJJAWI COLL APPL ENGN,IRBID,JORDAN

[2] JORDAN PETR REFINERY CO,DEPT HLTH,ZARKA,JORDAN

来源：

MUTATION RESEARCH | 1994年 / 312卷 / 02期

关键词：

CULTURED HUMAN LYMPHOCYTES; SISTER-CHROMATID EXCHANGES; OCCUPATIONAL EXPOSURE; OIL REFINING;

D O I：

10.1016/0165-1161(94)90024-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In order to assess the potential genotoxic effects of occupational exposure to petrochemicals, the incidence of sister-chromatid exchanges (SCE) in cultured lymphocytes was studied. Blood samples were taken from 233 individuals (184 exposed and 49 worksite controls) in an oil refinery and from 47 community control persons. The data showed a non-significant elevation of SCE frequency in occupationally exposed workers when compared to non-exposed individuals. The mean SCE frequency per cell ranged from 7.55 +/- 0.55 in blood of lube oil blending and canning (LOBC) workers to 9.13 +/- 0.71 in catalytic cracking and water treatment (CCWT) workers. The control values were 6.2 +/- 0.67 and 7.21 +/- 0.45 in the community and worksite individuals, respectively. Furthermore, the SCE frequencies were influenced neither by age nor by smoking.

引用

页码：187 / 191

页数：5

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