ADIPOKINETIC HORMONES - CELL AND MOLECULAR-BIOLOGY

被引：66

作者：

OSHEA, M

RAYNE, RC

机构：

[1] Sussex Centre for Neuroscience, School of Biological Sciences, University of Sussex, Brighton, BN1 9QG, Sussex, Falmer

来源：

EXPERIENTIA | 1992年 / 48卷 / 05期

关键词：

CORPUS CARDIACUM; NEUROPEPTIDE; ADIPOKINETIC HORMONE; PROHORMONE PROCESSING; SCHISTOCERCA-GREGARIA;

D O I：

10.1007/BF01928161

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Adipokinetic hormones AKH I (pGlu-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2) and AKH II (pGlu-Leu-Asn-Phe-Ser-Trp-Gly-Thr-NH2) are synthesized by neurosecretory cells (NSC) of the corpora cardiaca (CC) in the locust, Schistocerca gregaria. These NSC constitute a homogeneous 'peptide factory' as each cell synthesizes both AKH I and AKH II. This homogeneity makes the CC an excellent system in which to study aspects of neuropeptide biosynthesis. This report summarizes recent findings on AKH inactivation and metabolism, as weil as on AKH prohormone processing and biosynthesis.

引用

页码：430 / 438

页数：9

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