CHARACTERIZATION OF NORMAL HUMAN-CELLS BY PYROLYSIS-GAS CHROMATOGRAPHY-MASS SPECTROMETRY

被引：24

作者：

REINER, E ^{[1
]}

ABBEY, LE ^{[1
]}

MORAN, TF ^{[1
]}

PAPAMICHALIS, P ^{[1
]}

SCHAFER, RW ^{[1
]}

机构：

[1] GEORGIA INST TECHNOL,SCH ELECT ENGN,ATLANTA,GA 30332

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 11期

关键词：

D O I：

10.1002/bms.1200061107

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Differentiation of normal human cells has been accomplished by pyrolysis gas chromatography mass spectrometry. Normal cells from human kidney, spleen, liver and brain tissues have been pyrolyzed and the products chromatographically separated and characterized by mass spectrometry. Molecular pyrolysis products giving rise to the characteristic pyro‐mass chromatograms include, but are not limited to, alkenes, alkanes, nitriles and various ring compounds. Single ion mass chromatograms as well as multiple ion mass chromatograms have been used to explore the characteristic differences between various tissue materials. A dynamic computer methodology for comparing pyro‐mass chromatograms has been developed for use in automatic identification and classification of the human cellular material. Copyright © 1979 Heyden & Son Ltd

引用

页码：491 / 498

页数：8

共 30 条

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