ENZYME STABILIZATION WITHOUT CARRIERS

被引：81

作者：

TORCHILIN, VP

MARTINEK, K

机构：

[1] National Cardiology Research Centre, Academy of Medical Sciences USSR, Moscow

[2] Lomonosov State University, Moscow

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1979年 / 1卷 / 02期

关键词：

D O I：

10.1016/0141-0229(79)90102-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

This review deals with the problem of enzyme stabilization without the use of carriers. The following main types of stabilization are considered: addition of low-molecular weight compounds; addition of organic solvents; chemical modification of key functional groups on enzymes; intramolecular crosslinking with bifunctional reagents. The mechanisms of the procedures are discussed, and further methods for stabilizing enzymes without the use of carriers are suggested. © 1979.

引用

页码：74 / 82

页数：9

共 84 条

[1]

BEAVEN GH, 1973, INT J PEPT PROT RES, V5, P215

[2] CHEMICAL MODIFICATION AND CROSS-LINKING OF PROTEINS BY IMPURITIES IN GLYCEROL [J].